David Isaacs 
Evidence-Based Pediatric Infectious Diseases 

Evidence-based Pediatric Infectious Diseases is a practical
guide to the diagnosis and management of childhood infections in
clinical practice. Renowned Clinical Professor of Pediatric
Infectious Diseases, David Isaacs, and an expert consultant editor
team, bring you the first book to critically look at the evidence
for decision making in pediatric infections.

Based around illustrative case studies, each chapter presents
and analyzes current evidence on the management of different
pediatric infections and provides firm treatment recommendations
based on evidence of:

* efficacy and safety

* antibiotic resistance

* cost

* adverse effects

* ethical considerations.

Clear summaries and specific guidance allow you to assess the
evidence for yourself and make rapid but informed management
decisions based on the strength of evidence available. Antibiotic
doses are presented clearly and simply, enabling you to select
appropriate treatment at a glance.

This book uses a case-based approach that focuses on the most
common disease areas affecting children in industrialized
countries, developing countries, travelers and refugees. It is an
up-to-date, relevant and widely applicable text that carefully
examines the evidence for antibiotics and other interventions
whilst encouraging a conservative and responsible approach to
antibiotic use.

Evidence-based Pediatric Infectious Diseases is an
indispensable resource for any practitioner who strives to provide
the best evidence-based care for childhood infections.

Table of Content

About the authors.

Preface.

Acknowledgements.

Abbreviations.

1 Evidence-based practice.

2 Rational antibiotic use.

3 Cardiac infections.

4 Cervical infections.

5 Eye infections.

6 Fever.

7 Gastrointestinal infections.

8 HIV infection.

9 Immune deficiency.

10 Meningitis and central nervous system.

infections.

11 Osteomyelitis and septic arthritis.

12 Respiratory infections.

13 Sexually transmitted and genital infections.

14 Skin and soft tissue infections.

15 Systemic sepsis.

16 Tropical infections and travel.

17 Urinary tract infections.

18 Viral infections.

Appendix 1 Renal impairment and.

antimicrobials.

Appendix 2 Aminoglycosides: dosing and.

monitoring blood levels.

Appendix 3 Antimicrobial drug dose.

recommendations.

Index

About the author

David Isaacs is a senior staff physician in paediatric infectious
diseases and immunology at The Children’s Hospital at
Westmead, Sydney and Clinical Professor of Paediatric Diseases at
the University of Sydney. He has published 10 books and over 200
peer-reviewed publications. His research interests are neonatal
infections, respiratory virus infections, immunisations and ethics.
He also has published on medical ethics. Professor Isaacs is on
multiple national and international committees on infectious
diseases and immunisations and is a reviewer for the Cochrane
Collaboration.

Consultant Editors:

Elizabeth Elliott

Ruth Gilbert

Virginia Moyer

Michael Pichichero