Florinel-Gabriel Banica 
Chemical Sensors and Biosensors 
Fundamentals and Applications

Key features include:

* Self-assessment questions and exercises

* Chapters start with essential principles, then go on to address
more advanced topics

* More than 1300 references to direct the reader to key
literature and further reading

* Highly illustrated with 450 figures, including chemical
structures and reactions, functioning principles, constructive
details and response characteristics

Chemical sensors are self-contained analytical devices that
provide real-time information on chemical composition. A chemical
sensor integrates two distinct functions: recognition and
transduction. Such devices are widely used for a variety of
applications, including clinical analysis, environment monitoring
and monitoring of industrial processes. This text provides an
up-to-date survey of chemical sensor science and technology, with a
good balance between classical aspects and contemporary trends.
Topics covered include:

* Structure and properties of recognition materials and reagents,
including synthetic, biological and biomimetic materials,
microorganisms and whole-cells

* Physicochemical basis of various transduction methods
(electrical, thermal, electrochemical, optical, mechanical and
acoustic wave-based)

* Auxiliary materials used e.g. synthetic and natural polymers,
inorganic materials, semiconductors, carbon and metallic
materials

* properties and applications of advanced materials (particularly
nanomaterials) in the production of chemical sensors and
biosensors

* Advanced manufacturing methods

* Sensors obtained by combining particular transduction and
recognition methods

* Mathematical modeling of chemical sensor processes

Suitable as a textbook for graduate and final year undergraduate
students, and also for researchers in chemistry, biology, physics,
physiology, pharmacology and electronic engineering, this bookis
valuable to anyone interested in the field of chemical sensors and
biosensors.

Table of Content

1 What are Chemical Sensors? 1

2 Protein Structure and Properties 21

3 Enzymes and Enzymatic Sensors 28

4 Mathematical Modeling of Enzymatic Sensors 50

5 Materials and Methods in Chemical-Sensor Manufacturing 66

6 Affinity-Based Recognition 101

7 Nucleic Acids in Chemical Sensors 118

8 Nanomaterial Applications in Chemical Sensors 135

9 Thermochemical Sensors 157

10 Potentiometric Sensors 165

11 Chemical Sensors Based on Semiconductor Electronic Devices 217

12 Resistive Gas Sensors (Chemiresistors) 246

13 Dynamic Electrochemistry Transduction Methods 258

14 Amperometric Enzyme Sensors 314

15 Mathematical Modeling of Mediated Amperometric Enzyme Sensors 332

16 Electrochemical Affinity and Nucleic Acid Sensors 347

17 Electrical-Impedance-Based Sensors 367

18 Optical Sensors — Fundamentals 404

19 Optical Sensors — Applications 435

20 Nanomaterial Applications in Optical Transduction 454

21 Acoustic-Wave Sensors 473

22 Microcantilever Sensors 507

23 Chemical Sensors Based on Microorganisms, Living Cells and Tissues 518

Index 531

About the author

Dr Florinel-Gabriel BANICA is Associate Professor at the Norwegian University of Science and Technology, Dept of Chemistry. Prior to this he was at the Technical University of Bucharest, Romania. Florin’s research is focused on bioelectrochemistry, and functionalized materials for chemical sensor applications. He teaches undergraduate courses on analytical chemistry, instrumental analysis, electroanalytical chemistry and physical chemistry, and graduate courses on atomic spectrometry and chemical sensors and biosensors (on which this book is based).