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J.-C. Carel & Paul A. Kelly 
Deciphering Growth 

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Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism’s body size, which is not only limited to the size of the brain.

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Table of Content

Evolutionary Trends in Body Size.- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation.- Genetic Control of Size at Birth.- The GH/IGF-1 Axis: Insights from Animal Models.- Downstream Mechanisms of Growth Hormone Action.- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I.- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action.- IGF-I Deficiency: Lessons from Human Mutations.- Putting IGF-I Biology into a Clinical Perspective.- IGF Resistance: The Role of the Type 1 IGF Receptor.- The Importance of the National Cooperative Growth Study (NCGS).- Why we are Treating Children with Growth Hormone: Lessons from the French Registry.
Language English ● Format PDF ● Pages 155 ● ISBN 9783540289029 ● File size 3.2 MB ● Editor J.-C. Carel & Paul A. Kelly ● Publisher Springer Berlin ● City Heidelberg ● Country DE ● Published 2006 ● Downloadable 24 months ● Currency EUR ● ID 2161194 ● Copy protection Social DRM

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