Peter H. Schur & Elena M. Massarotti 
Lupus Erythematosus 
Clinical Evaluation and Treatment

Often considered the prototypic autoimmune disease, Lupus is characterized by protean manifestations and affects a wide range of organ systems. Despite widespread availability of anti nuclear antibody testing and other technological diagnostic advances, the diagnosis of lupus can be elusive, difficult, and inexact. Treatment of the disease can also be challenging. Advances in immunology and biotechnology have led to a burgeoning world of new therapies in development that offer patients the real possibility of new therapies and physicians and scientists novel insights into the pathogenesis of this complicated immunological disease.
Lupus Erythematosus: Clinical Evaluation and Treatment summarizes the clinical aspects of lupus facing the general clinician in the 21
st century. In this invaluable, practical book, the reader will find introductory chapters regarding general diagnostic and treatment principles, followed by chapters addressing the lupus-specific organ manifestations. Special topics regarding pregnancy and comorbidities are also presented. Written by highly experienced physicians with special expertise in lupus,
Lupus Erythematosus: Clinical Evaluation and Treatment is an indispensable reference for the common and not so common problems affecting patients with lupus.

Table of Content

Introduction

      EM Massarotti and PH Schur

 

1. SLE Epidemiology: Epidemiology Subtypes and Risk Factors for Development

      JF Simard,  and KH Costenbader

 

2. The Immunopathogenesis and Immunopathology of SLE

        D Pisetsky

 

3. Diagnosis and Monitoring SLE

      PH Schur

 

4. Clinical Monitoring of the Patient with Lupus

             VP Bykerk

 

5. The Treatment of SLE: General Principles

       EM Massarotti and PH Schur

 

6. Cutaneous Manifestations of Lupus Erythematosus

       H Townsend, and  RA Vleugels

 

7. Musculoskeletal Manifestations of SLE

       S Helfgott

 

8. The Cerebrovascular System in SLE

      R Sands

 

9. Pulmonary Manifestations of SLE

      HJ Goldberg, and PF Dellaripa

 

10. Hematologic Manifestations of SLE

        N Berliner

 

11. Renal Manifestations of SLE

      M Dooley

 

12. Gastrointestinal Manifestations of SLE

       RS Kalman and J Wolf

 

13. Neuropsychiatric Aspects of SLE

       S Khoshbin

 

14. SLE and Pregnancy

    B Bermas

 

15. Anti-phospholipid Antibody Syndrome

    B Bermas

 

16. Lupus-Like Syndromes related to Drugs

        J Merola

 

17. New and Emerging Therapies for SLE

     EM Massarotti

 

18. Comorbidities in SLE

       M Gayed, C-S Yee, S Bernatsky, C Gordon