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Richard A. Hopkins 
Cardiac Reconstructions with Allograft Tissues 

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Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition (‘Cardiac Reconstructions with Allograft Valves’) in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table. All surgeons performing pediatric and/or adult valve replacements and reconstructive cardiac surgeries will benefit from the described methods. Cardiothoracic residents and cardiologists will also find the text useful. It will provide the surgeon with an enhanced understanding of the biological and material properties of allografts and increased familiarity with the range of surgical techniques applicable for the use of these valves, particularly in the successful management of challenging cardiac reconstructions.>

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Table of Content

Preface to the Second Edition Preface to the First Edition Acknowledgments Contributors Section I Original Principles 1 The Use of Homograft Valves: Historical Perspective Richard A. Hopkins Section II Major Clinical Series of Homograft Valve Transplants: Left Ventricular Outflow Tract 2 Mayo Clinic Series Robert B. Wallace and Thomas A. Orszulak 3 University of Alabama at Birmingham Series David C. Mc Giffin and James K. Kirklin 4 Modified Root Replacement Concept: Influence of Implant Technique on Allograft Durability William W. Angell and Aubyn Marath Section III Major Clinical Series of Homograft Valve Transplants: Right Ventricular Outflow Tract 5 Great Ormond Street Series Jaroslav Stark and Mila Stajevic-Popovic 6 Denver Series David R. Clarke and Deborah A. Bishop 7 Toronto Series William G. Williams Section IV Cryopreserved Allograft Tissue for Cardiac Reconstruction 8 Cryopreserved Cardiac Valves: Initial Experiences and Theories Richard A. Hopkins 9 Surgery for Infections David C. Mc Giffin and James K. Kirklin 10 Pulmonary Valve Autotransplant Procedure: Clinical Results Compared with Other Methods for Aortic Valve Replacement Erle H. Austin, III 11 In Vivo Pulsatile Hemodynamics of Homografts Jeff Myers and Richard A. Hopkins Section V Cell Biology of Heart Valve Leaflets 12 Leaflet Endothelium Flavian M. Lupinetti 13 Leaflet Interstitial Cells Robert H. Messier, Jr., Patrick W. Domkowski, and Richard A. Hopkins 14 Leaflet Intersitial Cell Growth and Recovery Robert H. Messier, Jr., Diane Hoffman-Kim, and Richard A. Hopkins 15 Activation of the Immune System by Cardiac Valve Allografts Franciska Hoekstra, Christiaan Knoop, Ad Bogers, and Willem Weimar Section VICryobiology of Heart Valve Preservation 16 Application of Cryopreservation to Heart Valves Lloyd Wolfinbarger, Jr., Kelvin G.M. Brockbank, and Richard A. Hopkins 17 Cell Viability and Problems with Its Quantification Diane Hoffman-Kim and Richard A. Hopkins 18 Factors Affecting Cellular Viability During Preimplantation Processing Richard A. Hopkins, Diane Hoffman-Kim, Robert H. Messier, Jr., and Patrick W. Domkowski 19 Cell Origins and Fates Following Transplantation of Cryopreserved Allografts M.G. Hazekamp, D.R. Koolbergen, J. Braun, J.A. Bruin, C.J. Cornelisse, Y.A. Goffin, and H.A. Huysmans 20 Resolution of the Conflicting Theories of Prolonged Cell Viability Richard A. Hopkins Section VII Allograft Heart Valves: Morphologic, Biochemical, and Explant Pathology Studies 21 Overview Stephen L. Hilbert, Fred Schöen, and Victor Ferrans 22 Morphology Stephen L. Hilbert, Fred Schöen, and Victor Ferrans 23 Biomechanics Stephen L. Hilbert, Fred Schöen, and Victor Ferrans 24 Effects of Preimplantation Processing on Allograft Valves Stephen L. Hilbert, Fred Schöen, and Victor Ferrans 25 Explant Pathology Studies Stephen L. Hilbert, Fred Schöen, and Victor Ferrans 26 Implications of Explant Pathology Studies Stephen L. Hilbert, Fred Schöen, and Victor Ferrans Section VIII Allograft Valve Banking: Harvest and Cryopreservation Techniques 27 Cryopreservation and Tissue Banking Perry L. Lange and Richard A. Hopkins 28 Donor Suitability and Heart Procurement Scott A. Brubaker 29 Techniques and Technology: Dissection, Examination, Sterilization, and Cryopreservation Mark Van Allman and Kelvin G. M. Brockbank 30 Techniques and Technology: Storage, Transportation and Distribution, Thawing and Dilution, and Quality Systems Perry L. Lange and Kelvin G. M.
Language English ● Format PDF ● Pages 656 ● ISBN 9780387265155 ● File size 27.8 MB ● Publisher Springer New York ● City NY ● Country US ● Published 2005 ● Downloadable 24 months ● Currency EUR ● ID 2144276 ● Copy protection Adobe DRM
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