Annie Young & Richard Hobbs 
ABC of Colorectal Cancer 

Colorectal cancer is a common cause of morbidity and mortality in
which prevention, screening and early detection are vital.
Beginning with the patient perspective and following the patient
pathway, this new second edition covers epidemiology and
prevention, screening programmes, decision support networks, the
role of primary care, and supportive care for patients with
colorectal cancer.

The ABC of Colorectal Cancer provides the core knowledge
on clinical genetics, diagnosis, imaging, therapy and surgery
options and the latest evidence based guidelines for treating and
managing colorectal cancer patients within the multidisciplinary
team. Highly illustrated and accessible, it covers the full
spectrum of the disease to provide the basis to make a real
difference to clinical management.

This is an invaluable practical guide for the non-specialist on
all aspects of colorectal cancer, and is ideal for general
practitioners, junior doctors, nurses and allied health
professionals.

Table of Content

Contributors vii

Preface ix

1 The Patient Perspective 1
Kevin Bond

2 Epidemiology and Prevention 4
Peter Boyle, Patrick Mullie, Maria Paula Curado and David Zaridze

3 Pathways of Carcinogenesis 8
Michael Christie and Oliver Sieber

4 Clinical Genetics in the Management of Colon Cancer 13
Kai Ren Ong, Vicky Bowyer and Trevor Cole

5 Screening for Colorectal Cancer 19
Julietta Patnick and Wendy S. Atkin

6 Decision Support Networks 22
Matthew Kelly, Mark Austin and Sir Michael Brady

7 Pathology of Colorectal Cancer 26
Mohammad Ilyas

8 Imaging of Colorectal Cancer 31
Andrew Slater

9 The Role of Primary Care 36
Sue Wilson and Richard Hobbs

10 Radiotherapy for Rectal Cancer 40
Andrew Weaver

11 Surgical Interventions 44
Shazad Ashraf and Neil Mortensen

12 Adjuvant Therapy 48
Zenia Saridaki-Zoras and David Kerr

13 Treatment of Advanced Disease 52
David Watkins and David Cunningham

14 Innovative Treatment for Colorectal Cancer 58
Joanne L. Brady and David Kerr

15 Supportive Care for Patients with Colorectal Cancer 63
Pauline Mc Culloch and Annie Young

16 Follow-up 69
John Primrose

Index 74

About the author

Annie Young, Professor of Nursing, Warwick Medical School, The University of Warwick, Coventry

Richard Hobbs, Professor and Head of Primary Care Health Sciences, Department of Primary Care Health Sciences, University of Oxford

David Kerr, Professor of Cancer Medicine, Nuffield Dept of Clinical and Laboratory Sciences, University of Oxford