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José Marín-García
Aging and the Heart
A Post-Genomic View

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In this book, the genetic and molecular basis of cardiovascular aging is examined in detail and a comprehensive assessment given of the bioenergetics changes occurring in human and animal models of cardiac aging. Both current diagnostic and future therapeutic modalities are presented, giving this book a dual-pronged approach. Cardiac aging, like aging in general, is a complex process involving numerous cellular and molecular changes. This book sheds new light on the phenomenon.

€106.99

Table of Content

Preface.- Section I. Introduction to A Post-Genomic View of Aging and the Aging Heart: Post-Genomic View of Aging: Definitions, Theories and Observations.- Overview of Cardiovascular Aging.- Section II. Methodologies, Cardiac Phenotypes And Adaptation: Molecular and Cellular Methodologies.- Molecular And Cellular Phenotypes of Cardiac Aging.- Section III. Aging of the Cardiovasculature and Related Systems: Aging of the Vasculature.- Aging of Cardiovascular-Related Systems.- Section IV. Cardiovascular Diseases in Aging: Cardiomyopathy and Heart Failure in Aging.- Atherosclerosis, Hypertension and Aging.- Metabolic Syndrome, Diabetes and Cardiometabolic Risks in Aging.- Gender and Cardiovascular Aging.- Cardiac Dysrhythmias and Channelopathies in Aging.- Section V. Genetics: Genetics of Life Span: Lessons from Model Organisms.- Profiling the Aging Cardiovascular System: Transcriptional, Proteomic, SNP, Gene Mapping and Epigenetics Analysis.- Section VI. Therapies: Translational Research: Pharmacogenomics, Gene and Cell-Based Therapy in the Aging Cardiovascular System.- Nutrition and Exercise in Cardiovascular Aging: Metabolic and Pharmacological Interventions.- Section VII. The Future of Aging Research: Aging and the Frontier ahead.- Glossary.- Index.

Language English ● Format PDF ● Pages 568 ● ISBN 9780387740720 ● File size 6.5 MB ● Publisher Springer US ● City NY ● Country US ● Published 2007 ● Downloadable 24 months ● Currency EUR ● ID 2145860 ● Copy protection Adobe DRM

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