This book is a comprehensive guide to our current understanding of idiopathic pulmonary fibrosis (IPF), its disease pathogenesis, genetic underpinnings, diagnosis, and management. Since the first edition, many new developments have occurred in the understanding and management of this serious disease, revising our understanding of how it presents, manifests, and reacts to certain treatments. This second edition is fully updated with six new chapters by our team of international, expert authors. New topics include: classification of interstitial lung disease, pulmonary function tests in IPF, biomarkers, clinical phenotypes, mimics, and a discussion of clinical trials. Each chapter additionally includes a brief summary of ongoing research and potential future directions. Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide, Second Edition is an invaluable resource for clinicians who desire a deeper understanding of IPF in order to better help their patients.
Table of Content
Classification and Nomenclature of Interstitial Lung Disease.- Epidemiology and Natural History of IPF.- Histopathology of IPF and Related Disorders.- Imaging of IPF.- Pulmonary Function Tests in Idiopathic Pulmonary Fibrosis.- The Role of Immunity and Inflammation in IPF Pathogenesis.- Mechanisms of Fibrosis in IPF.- The Genetics of Pulmonary Fibrosis.- Genomics and Epigenetics of Pulmonary Fibrosis.- Biomarkers and IPF.- Clinical Phenotypes and Co-morbidities in IPF.- The Keys to Making a Confident Diagnosis of IPF.- Pharmacologic Treatment of IPF.- Mimics of IPF.- Gastroesophageal Reflux and IPF.- The Role of Pulmonary Rehabilitation and Oxygen Therapy.- Acute Exacerbations of IPF.- Lung Transplantation for IPF.- Clinical Trials in IFP: What are the Best Endpoints?.- Future Directions for IPF Research.
About the author
Keith C. Meyer, MD is a professor of pulmonary and critical care medicine at the University of Wisconsin School of Medicine and Public Health. He is volume editor of three successful Springer books: Idiopathic Pulmonary Fibrosis, Gastroesophageal Reflux and the Lung, and Bronchiolitis Obliterans Syndrome in Lung Transplantation.Steven D. Nathan, MD is professor of medicine at Virginia Commonwealth University Inova Campus and director of the Lung Transplant and Advanced Lung Disease programs. He is also volume editor of Idiopathic Pulmonary Fibrosis and the upcoming Guide to Clinical Management of Idiopathic Pulmonary Fibrosis (with Springer Healthcare)
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