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Linda M. Collins & Kari C. Kugler 
Optimization of Behavioral, Biobehavioral, and Biomedical Interventions 
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Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities.  These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement.  


This book provides additional information on a principled empirical framework for developing interventions that are more effective, efficient, economical, and scalable.  This framework is introduced in the monograph, ‘Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy (MOST)’ by Linda M. Collins (Springer, 2018).  The present book is focused on advanced topics related to MOST.   The chapters, all written by experts, are devoted to topics ranging from experimental design and data analysis to development of a conceptual model and implementation of a complex experiment in the field. Intervention scientists who are preparing to apply MOST will find this book an important reference and guide for their research.  Fields to which this work pertains include public health (medicine, nursing, health economics, implementation sciences), behavioral sciences (psychology, criminal justice), statistics, and education.


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Table of Content

1. Using the Multiphase Optimization Strategy (MOST) to Develop an Optimized Online STI Preventive Intervention Aimed at College Students: Description of Conceptual Model and Iterative Approach to Optimization.- 2. implementing factorial experiments in real-world settings: Lessons learned while engineering an optimized smoking cessation treatment.- 3. Multilevel Factorial Designs in Intervention Development.- 4. Experimental Designs for Research on Adaptive Interventions: Singly and Sequentially Randomized Trials.- 5. Intensively Adaptive Interventions Using Control Systems Engineering: Two Illustrative Examples.- 6. Coding and interpretation of effects in analysis of data from a factorial experiment.- 7. Optimizing the Cost-Effectiveness of a Multicomponent Intervention Using Data from a Factorial Experiment: Considerations, Open Questions, and Tradeoffs Among Multiple Outcome.- 8. Investigating an Intervention’s Causal Story: Mediation Analysis Using a Factorial Experiment and Multiple Mediators.

About the author



Linda M. Collins is Distinguished Professor of Human Development and Family Studies, Professor of Statistics, and the director of The Methodology Center at the Pennsylvania State University. She is interested in most aspects of research methods.  Her current work focuses on experimental and non-experimental design, particularly for building, optimizing and evaluating behavioral, biobehavioral, and biomedical interventions. Professor Collins also has a long-standing interest in models for longitudinal data, particularly latent transition analysis, and other latent class models.





Kari C. Kugler is an Assistant Teaching Professor in Biobehavioral Health and an Affiliate of the Methodology Center at Penn State. Trained as a behavioral epidemiologist, her work focuses on the design and analysis of multi-component, multi-level interventions targeting a wide range of health behaviors among various populations and contexts.  She collaborates with intervention scientists on building highly effective and efficient behavioral interventions.







Language English ● Format PDF ● Pages 301 ● ISBN 9783319917764 ● File size 5.9 MB ● Editor Linda M. Collins & Kari C. Kugler ● Publisher Springer International Publishing ● City Cham ● Country CH ● Published 2018 ● Downloadable 24 months ● Currency EUR ● ID 6438332 ● Copy protection Social DRM

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