Manfred Schlosser 
Organometallics in Synthesis 
Third Manual

WINNER of the 2013 PROSE Award in Chemistry &
Physics

This latest edition enables readers to master new classes of
organometallic compounds and syntheses

A popular resource used by synthetic organic chemists around the
world, this book enables readers to conduct seamless synthetic
reactions involving key organometallics. Each reaction is set forth
in the book’s acclaimed recipe-style format so that readers can
easily replicate the results in their own labs. Moreover, each
chapter has been written by a world leader in the field of
organometallics in organic synthesis. These authors offer hands-on
guidance and practical examples illustrating the preparation of
organometallics and its application in organic synthesis.

This Third Manual of Organometallics in Synthesis
features completely new content and topics, with an eye towards
providing researchers with the most useful and practical reference
on the synthesis of organometallics. Organized into chapters by
type of organometallic compound, the book covers:

* Organoalkali chemistry

* Organomagnesium and organozinc chemistry

* Organosilicon and relating organotin chemistry

* Organoiron chemistry

* Organopalladium chemistry

Within each chapter, readers will find background information to
learn more about the class of organometallics as well as
mechanistic considerations. The authors thoroughly discuss the
various methods of preparing the organometallic compounds presented
in the book and outline their uses in synthetic reactions. In
addition to current applications, the authors explore future
research opportunities for each organometallic class. References at
the end of each chapter enable readers to explore all the topics in
greater depth.

More and more industrial processes rely on organometallic
chemistry. As a result, readers will find this book’s step-by-step
instructions essential in such fields as natural product synthesis,
pharmaceuticals, fine chemicals, biotechnology, polymers, and
materials science.

Table of Content

List of Contributors VII

Preface IX

Organoalkali Chemistry 1

Manfred Schlosser

Organomagnesium and Organozink Chemistry 223

Paul Knochel

Organosilicium and Organotin Chemistry 373

Tamejiro Hiyama

Organoiron Chemistry 545

Hans-Joachim Knölker

Organopalladium Chemistry 777

Stefan Bräse

Index 1001

About the author

MANFRED SCHLOSSER, Ph D, is Emeritus Professor of
Chemistry at the Swiss Federal Institute of Technology in Lausanne,
Switzerland. His research examines the intersection between
physical organic chemistry and applied synthesis. In addition to
editing the previous editions of Organometallics in
Synthesis, Dr. Schlosser has authored over 300 original
research articles and thirty-four monographs and reviews.