Gunther Bastert & Ingo J. Diel 
Metastatic Bone Disease 
Fundamental and Clinical Aspects

"Metastatic Bone Disease: Fundamental and Clinical Aspects"is an expanded version of a workshop on bone metastaseswhich was held in Heidelberg, Germany, in April 1993. Bonemetastases very often develop from malignant tumors and leadto complications which considerably diminish the quality oflife of the patient. Bone pain, pathological fractures, andhypercalcemic syndrome should be recognized and treated ear-ly, so as to prevent any further morbidity and immobilizati-on. Antiosteolytic substances such as biophosphonate cansupplement the established palliative and supportive thera-pies. Highly qualified basic researchers and clinicians inpathophysiology, diagnosis, and treatment of metastatic bonedisease have contributed to this book, providing a goodoverview ofpresent knowledge and research. The book will beof interest not only to specialists, but also to any physi-cian interested in oncology.