Mohit Bhandari & Bernd Robioneck 
Advanced Concepts in Surgical Research 

<p><strong><em>A practical, all-inclusive roadmap to understanding and executing advanced surgical research</em></strong></p><p><em>Advanced Concepts in Surgical Research</em> is a practical, reader-friendly guide to planning, conducting, and evaluating solid, evidence-based surgical research that leads to high-quality results. Geared to the investigator who has already mastered basic principles, this book focuses on more advanced topics such as randomized controlled trials, survey design, observational studies, meta analyses, statistical concepts, reporting of data, and much more.</p><p><strong>Special Features:</strong></p><UL><LI>Includes tips and insights from experienced surgical researchers on how to conduct an effective clinical study and avoid pitfalls</LI><LI>Supplies hard-to-find information on current topics such as randomization systems and technology and publication bias</LI><LI>Provides standardized, easy-to-reference text boxes with highlighted key concepts, on-the-spot definitions of terminology in Jargon Simplified sections, and real-world case examples from the literature</LI><LI>Presents nearly 60 illustrations and tables to help in visualizing key concepts</LI></UL><p>Filled with proven research methodologies, clinical data, examples, and strategies that can be applied across a wide range of disciplines, <em>Advanced Concepts in Surgical Research</em> illuminates the challenges and solutions of modern day surgical research. It is essential for any clinician undertaking a well-defined, systematic, clinically relevant, and ultimately successful surgical research study.</p>

Innehållsförteckning

<p>1 Factorial Randomized Trials<br>2 Expertise-Based Randomized Trials<br>3 Randomization Systems and Technology<br>4 Blinding and Concealment<br>5 Composite Outcome in Orthopaedics: Understanding the Concepts<br>6 Adjudication of Outcomes&mdash;Systems and Approaches<br>7 Subgroup Analyses<br>8 Trial Management&mdash;Advanced Concepts and Systems<br>9 Case&ndash;Control Studies<br>10 Cohort Studies<br>11 Survey Design<br>12 Qualitative Studies<br>13 Economic Analysis<br>14 Literature Searches<br>15 Understanding Effect Sizes<br>16 Fixed Effects versus Random Effects<br>17 Heterogeneity<br>18 Uncovering Publication Bias<br>19 Statistical Pooling&mdash;Programs and Systems<br>20 Meta-analysis of Observations Studies<br>21 Meta-regression<br>22 Preparing a Statistical Analysis Plan<br>23 Regression Analysis<br>24 Survival Analysis<br>25 Interim Analyses in Randomized Trials<br>26 Conflicts of Interest Reporting<br>27 Authorship&mdash;Modern Approaches and Reporting<br>28 Randomized Trials Reporting Checklists<br>29 Observational Studies Reporting Checklists<br>30 Meta-analysis Reporting Checklists<br>Resources and Contacts for Surgical Research<br>Glossary of Terms</p>