Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function.
Innehållsförteckning
Introduction.- From genomes to protein functions.- Co-evolutionary signals within genome sequences reflect functional dependence of proteins.- Chromosomal proximity of genes as an indicator of functional linkage.- Analyses of complex genome-scale biological networks.- Applications of protein interaction networks.
Språk Engelska ● Formatera PDF ● Sidor 60 ● ISBN 9781461447054 ● Filstorlek 1.6 MB ● Utgivare Springer New York ● Stad NY ● Land US ● Publicerad 2012 ● Nedladdningsbara 24 månader ● Valuta EUR ● ID 2662801 ● Kopieringsskydd Social DRM