Joyce C. Harper & Joy D. A. Delhanty 
Preimplantation Genetic Diagnosis 

Preimplantation Genetic Diagnosis (PGD) is the detection and
screening of genetic abnormality in gametes prior to fertilisation
and embryos fertilised in vitro prior to implantation. This
exciting new text provides an introduction and overview of the
principles of PGD.

An exciting fusion of prenatal diagnosis (PD) with in vitro
fertilisation (IVF), this book is will appeal to both the prenatal
diagnosis community, of clinical geneticists and foetal medicine
specialists within obstetrics and gynaecology, and the IVF
community within reproductive medicine. It is also an essential
introduction to PD, clinical genetics and IVF for non-specialists.

* A concise introduction to the field of PGD

* Detailed explanations of the techniques and procedures
used

* The law and ethical implications of PGD

* Future uses of PGD

表中的内容

List of Contributors.

Foreword.

BACKGROUND.

Introduction (J. Harper).

Genetic Basis of Inherited Disease (J. Delhanty).

Prenatal Diagnosis (A. Cockell & C. Rodeck).

Genetic Counselling (S. Raeburn).

In Vitro Fertilization (K. Elder).

Gametogenesis and Preimplantation Embryo Development (K. Elder
& S. Fleming).

Preimplantation Genetics (E. Pergament, et al.).

PROCEDURES USED IN PGD.

Clinical Aspects of Preimplantation Diagnosis (C. Overton, et
al.).

Embryo Biopsy (J. Harper & A. Thornhill).

Diagnosis of Single Gene Disorders (D. Wells & J.
Sherlock).

FISH and Embryo Sexing to Avoid X-linked Disease (J. Harper &
L. Wilton).

Preimplantation Genetic Diagnosis of Chromosome Abnormalities:
Specific Chromosomal Rearrangements and Age-related Aneuploidy (J.
Delhanty & C. Conn).

THE FUTURE.

Ethical Perspectives and Regulation of Preimplantation Genetic
Diagnostic Practice (S. Viville, et al.).

Future Developments in PGD (J. Harper & D. Wells).

Index.

关于作者

Joyce C. Harper has been working in the fields of IVF and reproductive genetics since 1987. After completing her Ph D at Kings College London, she worked as the Laboratory Director at the London Fertility Centre with Ian Craft and then joined the Hammersmith Hospital preimplantation genetic diagnosis.

Joy D. A. Delhanty is the editor of Preimplantation Genetic Diagnosis, published by Wiley.

Alan H. Handyside is the editor of Preimplantation Genetic Diagnosis, published by Wiley.