Denis Johnson 
Angels 

A dazzling and savage first novel New York Times Angels tells the story of two born losers. Jamie has ditched her husband and is running away with her two baby girls. Bill is dreaming of making it big in a life of crime. They meet on a Greyhound bus and decide to team up. So begins a stunning, tragic odyssey through the dark underbelly of America the bars, bus stations, mental wards and prisons that play host to Jamie and Bill as they find themselves trapped in a downward spiral though rape, alcohol, drugs and crime, to madness and death.From the author of Tree of Smoke, winner of the National Book Award for Fiction