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Neuroendocrine Correlates of Sleep/Wakefulness 

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As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management.


 


From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field.


Anyone who regularly reads the literature on sleep, biological rhythms, or neuroendocrinology is aware that one of the subspecialties within sleep medicine, the neuroendocrine correlates of sleep/wakefulness, has in particular experienced a growth rate that is even faster than that of the field as a whole. To a significant extent this has been due to the introduction of new research technologies.



The widespread adoption of a range of new methods in sleep research has opened a window into activities at the cellular and molecular level, which previously had been tightly closed. Consequently these activities are being characterized with a degree of precision and sensitivity that is without precedent. This volume invites the reader to explore the new vistas that have been opened onto the neuroendocrine frontier of sleep medicine. The editors have selectively identified a number of key articles having a citation frequency, which is considerably above the norm or which otherwise have contributed importantly to defining the neuroendocrine perspective.



This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology. Its coverage is broad and its basic


and clinical science reviews are detailed.



In this volume, an international team of experts discuss their latest ideas, concepts, methods, and interpretations with supporting examples. This volume is intended for advanced students and specialists in psychobiology, neuroscience, neuroendocrinology, and psychiatry but might also be interest to anyone concerned with understanding the Neuroendocrine correlates of sleep/wakefulness.



The contributions are directed more towards providing an integrated view of the field from the perspective of the authors, rather than being a compendium of recent results. The intent is to provide a reference book for recent and future workers in this and related areas of medicine and biology. Each topic in this volume has received the attention of a panel of authors who have responded to our request to review and place into perspective the major issues, which will undoubtedly confront newcomers to the field.



The topics dealt with in Neuroendocrine correlates of Sleep/wakefulness are both diverse and complex. The editors hope that this volume will provide an authoritative summary of important issues in the neuroendocrine correlates of sleep/wakefulness. We also hope that it will motivate new researchers to join the quest for solutions to the problems that have been identified by our contributing authors.

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Inhaltsverzeichnis

Biological Rhythms in Neuroendocrinology.- Basic Mechanisms Of Circadian Rhythms And Their Relation To The Sleep/Wake Cycle.- The Neuroendocrine Loop Model Revisited: Is It Valid Or Even Relevant?.- Biological Clock Control of Glucose Metabolism-Timing Metabolic homeostasis.- Molecular Mechanisms of Melatonin Action: Targets in Sleep Regulation.- The Developmental Regulation of Wake/Sleep System.- Serotonin and Neuroendocrine Regulation: Relevance to Sleep/Wake Cycle.- The Influence of Orexin on Sleep and Wakefulness.- Locus Coeruleus and Adrenergic Modulation of Rapid Eye Movement Sleep.- Neuroendocrine outcomes of Sleep Deprivation in Humans and Animals.- Sleep-Inductin Substances in the Regulation of Sleep.- Role of Pro-Inflammatory Ctokines in Sleep Disorders.- The Development and Regulation of Expressed Rhythmicity in Infants.- Autonomic Nervous System Activity During Sleep in Humans: Heart Rate Variability During Sleep.- Sleep and Circadian Rhythm of Melatonin in Smith-Magenis Syndrome.- Sleep and Circadian Rhythms in the Blind.- Melatonin, The Pineal Gland, and Headache Disorders.- THe Role of Melatonin in Sleep Regulation.- Melatonin in Circadian Rhythm Sleep Disorders.- Disturbances of Hormonal Circadian Rhythms in Shift Workers.- Endocrine Changes in Male Patients with Obstructuve Sleep Apnea.- Sleep-Disordreed Breathing and Hormones.- The Role of Peptides in Disturbed Sleep in Depression.- Neuroendocrine and Behavioral Correlates of Sleep Deprivation: A Synthesis of Neurobiological and Psychological Mechanisms.- Neuroendocrine Correlates of Sleep in Premenstrual, Pregnant, Postpartum and Menopausal Depression.- Sleep and Circadian Neuroendocrine Function in Seasonal Affective Disorder.- Neuroendocrine Correlates of Infectious Disease: Implications for Sleep.- Neuroendocrine Correlates of Restless Legs Syndrome.- Neuroendocrine and Neuroimmune Correlates of Narcolepsy.- Sleep disorders and Neuroendocrine Investigations: An Arctic Perspective
Sprache Englisch ● Format PDF ● Seiten 627 ● ISBN 9780387236926 ● Dateigröße 42.1 MB ● Verlag Springer US ● Ort NY ● Land US ● Erscheinungsjahr 2010 ● herunterladbar 24 Monate ● Währung EUR ● ID 2143992 ● Kopierschutz Adobe DRM
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