Hélène Pellissier & Alessandra Lattanzi 
Asymmetric Synthesis of Three-Membered Rings 

The first handbook to focus on the asymmetric synthesis of different types of three-membered rings.
The outstanding and experienced authors have an excellent international reputation and cover cyclopropanes, epoxides and aziridines as well as chiral oxaziridines in equal measure. To this end, they describe in detail different synthetic approaches starting with chiral substrates as well as the application of chiral metal- or organocatalysts. Furthermore, methods for the kinetic resolution of initially racemic products are treated alongside recent advances and novel developments in established techniques for the synthesis of three-membered rings.
With its structured composition this is of high interest to scientists in methodological and natural product synthesis as well as those in industrial and pharmaceutical chemistry.

Tabla de materias

CHAPTER 1: Asymmetric Cyclopropanations
1. Introduction
2. Simmons-Smith Cyclopropanation
3. Transition-Metal-Catalyzed Decomposition of Diazoalkanes
4. Michael-Initiated Ring Closure (MIRC)
5. Miscellaneous
6. Conclusion
CHAPTER 2: Asymmetric Aziridinations
1. Introduction
2. Aziridination Based on the Use of Chiral Substrates
3. Aziridination Based on the Use of Chiral Catalysts
4. Conclusion
CHAPTER 3: Asymmetric Epoxidations
1. Introduction
2. Epoxidation using Chiral Metal Catalysts
3. Epoxidation using Chiral Organocatalysts
4. Kinetic Resolutions
5. Epoxidation using Chiral Sulfur Ylides
6. Darzens Reaction
7. Conclusion
CHAPTER 4: Asymmetric Oxaziridinations
1. Introduction
2. Oxaziridination using Chiral Substrates
3. Oxaziridination using Chiral Catalysts
4. Kinetic Resolutions
5. Conclusion
General Conclusion

Sobre el autor

Hélène Pellissier is currently Chargée de Recherche (CNRS) at Aix Marseille Université (France). She carried out her Ph D under the supervision of Dr G. Gil in Marseille in 1987. After a postdoctoral period in Professor K. P. C. Vollhardt´s group at the University of California, Berkeley (USA), she joined the group of Professor M. Santelli in Marseille in 1992. She is the author of 95 papers including reviews in international journals, 7 books, and 6 book chapters.

Alessandra Lattanzi obtained the national Italian habilitation for Full Professor in organic chemistry in 2013 at the University of Salerno (Italy) and received her MSc and Ph D from University of Rome ‘La Sapienza’ (Italy). From 1999 to 2000 she was a visiting scientist in Prof. V. K. Aggarwal’s group in Sheffield (UK). In 2005, she was promoted to Associate Professor at the University of Salerno. She has authored over 95 publications including reviews in international journals, 12 book chapters in the areas of stereoselective synthesis of heterocyclic compounds and oxidation reactions.

Starting in 1983, Renato Dalpozzo was a Researcher of Organic Chemistry at the University of Bologna (Italy). In 1992, he moved to the University of Calabria (Italy) as Associate Professor of Organic Chemistry and then as Full Professor of Organic Chemistry. For ten years he was also full Professor of Environmental and Cultural Heritage Chemistry. He has authored over 110 publications and a book chapter in the areas of the reactivity of organometallic compounds with aromatic systems, the use of dianions derived from enamino carbonyl compounds, the stereoselective reduction of various classes of ketones, the development of new Lewis acid systems, and enantioselective organocatalysis. He authored also a text book for students of his University.