Damaraju Raghavarao & Lakshmi Padgett 
Repeated Measurements and Cross-Over Designs 

An introduction to state-of-the-art experimental design
approaches to better understand and interpret repeated measurement
data in cross-over designs.

Repeated Measurements and Cross-Over Designs:

* Features the close tie between the design, analysis, and
presentation of results

* Presents principles and rules that apply very generally to most
areas of research, such as clinical trials, agricultural
investigations, industrial procedures, quality control procedures,
and epidemiological studies

* Includes many practical examples, such as PK/PD studies in the
pharmaceutical industry, k-sample and one sample repeated
measurement designs for psychological studies, and residual
effects of different treatments in controlling conditions such as
asthma, blood pressure, and diabetes.

* Utilizes SAS(R) software to draw necessary inferences.
All SAS output and data sets are available via the book’s related
website.

This book is ideal for a broad audience including statisticians
in pre-clinical research, researchers in psychology, sociology,
politics, marketing, and engineering.

Circa l’autore

DAMARAJU RAGHAVARAO, Ph D, was Laura H. Carnell Professor
and Chairperson in the Department of Statistics at Temple
University. With more than fifty years of research experience in
all aspects of experimental design, sampling, and multivariate
analysis, Dr. Raghavarao authored eight additional books and over
135 journal articles throughout his career.

LAKSHMI PADGETT, Ph D, is Senior Manager at Janssen
R&D. Dr. Padgett has authored approximately twenty journal
articles, and her research interests include phase I, II, and III
trials.