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Toshio Nishikimi 
Adrenomedullin in Cardiovascular Disease 

Supporto

Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring c AMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases c AMP levels; indirectly reduces blood pressure and has role in the pathogenesis of arteriosclerosis.


Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

€106.99
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Tabella dei contenuti

Biochemistry of Adrenomedullin.- Adrenomedullin Receptor and Signal Transduction.- Adrenomedullin Gene.- Adrenomedullin Expression and Secretion.- Biological Action of Adrenomedullin.- Circulating Adrenomedullin.- Role of Adrenomedullin in Cardiovascular Diseases.- Adrenomedullin as an Adipokine.- Adrenomedullin Knockout Mouse and Transgenic Mouse.- Pleiotropic Effect of Adrenomedullin: Lessons from Pure Adrenomedullin Knockout Mouse.- Therapeutic Application of Adrenomedullin.- Therapeutic Potentials of Adrenomedullin for Heart Failure and Pulmonary Hypertension.

Circa l’autore

Toshio Nishikimi, MD, Ph D, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.
Lingua Inglese ● Formato PDF ● Pagine 219 ● ISBN 9780387254050 ● Dimensione 13.6 MB ● Editore Toshio Nishikimi ● Casa editrice Springer US ● Città NY ● Paese US ● Pubblicato 2005 ● Scaricabile 24 mesi ● Moneta EUR ● ID 2144141 ● Protezione dalla copia DRM sociale

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