Rat von Experten für die Vorbereitung, Durchführung und Auswertung von Tierstudien zur Entwicklung neuartiger Krebstherapien auf der Grundlage einer systematischen Analyse von Daten aus dem letzten Jahrzehnt.
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PrefaceIntroduction
Ethical Aspects of the Use of Animals in Translational Research
Study Design
Improving External Validity of Experimental Animal Data
How to End Selective Reporting in Animal Research
A Comprehensive Overview of Mouse Models in Oncology
Mouse Models of Advanced Spontaneous Metastasis for Experimental Therapeutics
Spontaneous Animal Tumor Models
Dog Models of Naturally Occurring Cancer
Improving Preclinical Cancer Models: Lessons from Human and Canine Clinical Trials of Metronomic Chemotherapy
Index
O autorze
Marianne Martic is a senior assistant at the Transdisciplinary Laboratorium Collegium Helveticum, a joint institution of the Swiss Federal Institute of Technolgy (ETH) and the University of Zurich (UZH). She joined the institution after obtaining her degree at the radiopharmaceutical institute of ETH Zürich, where she has worked on animal experimental protocols in the field of positron emission tomography (PET). Her current research is focused on the systematic reviewing and meta-analysis of preclinical animal experiments.August Schubiger is a senior fellow at the Transdisciplinary Laboratorium Collegium Helveticum, a joint institution of ETH and UZH. He has been full Professor of Radiopharmacy at the Institute of Pharmaceutical Sciences at ETH Zurich and headed the Center for Radiopharmaceutical Science of the ETH, the Paul Scherrer Institute (PSI) and at the Clinic and Polyclinic for Nuclear Medicine at the UZH until 2010. He is currently involved in the project 'Drug development – significance and predictive value of animal testing’.
Język Angielski ● Format PDF ● Strony 251 ● ISBN 9783527695911 ● Rozmiar pliku 4.7 MB ● Redaktor Marianne I. Martic-Kehl & P. August Schubiger ● Wydawca Wiley-VCH ● Opublikowany 2016 ● Ydanie 1 ● Do pobrania 24 miesięcy ● Waluta EUR ● ID 4964072 ● Ochrona przed kopiowaniem Adobe DRM
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