Stefan G. Hofmann 
Psychobiological Approaches for Anxiety Disorders 
Treatment Combination Strategies

Psychobiological Approaches for Anxiety Disorders presents a
comprehensive overview of the latest empirical evidence and
research results on combining pharmacological agents and CBT
techniques for the treatment of anxiety disorders.



* The first book to focus on the issue of enhancing CBT with
pharmacological agents

* Features chapters from leading authors in the fields of
psychiatry, pharmacology, clinical psychology, neuroscience, and
emotion research

* Contributes significantly to the field by summarizing the
contemporary research in combination treatments in anxiety
disorders

* A valuable resource for clinicians in training, as well as
experienced clinicians seeking to help patients with anxiety
disorders

Table of Content

About the Contributors vii

About the Editor xi

Introduction 1

Stefan G. Hofmann

Chapter 1 The Biology and Efficacy of Combination Strategies for
Anxiety Disorders 5

Keith A. Ganasen and Dan J. Stein

Chapter 2 Benzodiazepines 25

Bridget A. Hearon and Michael W. Otto

Chapter 3 Tricyclic Antidepressants and Monoamine Oxidase
Inhibitors 41

Franklin R. Schneier

Chapter 4 Selective Serotonin Reuptake Inhibitors, Reversible
Inhibitors of Monoamine Oxidase-A, and
Buspirone 61

Borwin Bandelow, Markus Reitt, and Dirk Wedekind

Chapter 5 D-Cycloserine 75

Adam J. Guastella and Gail A. Alvares

Chapter 6 Yohimbine Hydrochloride 91

Samantha G. Farris, Michelle L. Davis, Lindsey B. De Boer, Jasper
A. J. Smits, and Mark B. Powers

Chapter 7 Cortisol 109

Leila Maria Soravia and Dominique J.-F. de Quervain

Chapter 8 Oxytocin 123

Markus Heinrichs, Frances S. Chen, and Gregor Domes

Chapter 9 Dietary Supplements 145

Lindsey B. De Boer, Michelle L. Davis, Mark B. Powers, and Jasper
A. J. Smits

Chapter 10 A Roadmap for the Research and Practice of
Combination Strategies 181

Stefan G. Hofmann

Index 195

About the author

Stefan G. Hofmann is Professor of Psychology at Boston University and the Director of the Psychotherapy and Emotion Research Laboratory. The incoming President of the Association for Behavioral and Cognitive Therapies, he is widely published with more than 200 peer-reviewed journal articles and book chapters, and 10 books, including An Introduction to Modern CBT (2011, Wiley-Blackwell).