Nicolas Bogliotti & Roba Moumné 
Multi-Step Organic Synthesis 
A Guide Through Experiments

Dieses Lehrbuch verbindet Grundlagen, praktische Erkenntnisse und Strukturaufklärung. Präsentiert werden 16 Fallbeispiele, die jeweils auf veröffentlichten Forschungsartikeln beruhen und die Studierenden motivieren sollen, praktische Probleme in der organischen Synthese zu lösen.

Innehållsförteckning

Preface
1) Atovaquone: An Antipneumocystic Agent
2) SEN794: A SMO Receptor Antagonist
3) Synthesis of a H1-H3 Antagonist
4) Synthesis of Eletriptan
5) Total Synthesis and Structure Revision of Streptophenazine A
6) Synthesis of Leiodermatolide: A Biologically Active Macrolide
7) Azobenzene-Thiourea Catalysts for the Control of Chemical Reactivity with Light
8) Synthesis and Properties of a Photo-activatable Mimic of Pyridoxal 5′-Phosphate
9) Fluorescent Peptides for Monitoring Activity of Autophagy-Initiating Enzyme
10) Fluorescent Peptide Probes for Cathepsin B
11) Total Synthesis of Stemoamide
12) Total Synthesis and Structure Revision of Caraphenol B
13) Synthetic Routes Towards Muricatacin and Analogs
14) Asymmetric Synthesis of (-)-Martinellic Acid
15) Cyclic Pseudopeptides as Potent Integrin Antagonists
16) Enantioselective Synthesis of Nonnatural Amno Acids for Incorporation in Antimicrobial Peptides
Further Reading

Om författaren

Nicolas Bogliotti is Assistant Professor at École normale supérieure Paris-Saclay, France. After his undergraduate studies at Université Nice Sophia-Antipolis, France, he obtained his MSc and Ph D Degrees at Université Pierre et Marie Curie in Paris, France. He was a postdoc at ETH Zürich, Switzerland and Institut Curie, France, before his current position. His research interests focus on the synthesis of photosensitive molecules allowing visualization of recognition events, induction of a biological response and modulation of chemical reactivity.

Roba Moumné is Assistant Professor at Université Pierre et Marie Curie, France. She studied chemistry and completed her MSc and Ph D at the same university. Before her current position, she was also a postdoctoral fellow at Max-Planck-Institut in Mülheim and der Ruhr, Germany, at University of Zürich, Switzerland and at Université Paris Descartes, France. Her research interests include bioorganic chemistry and peptide synthesis.