Leena Peltonen 
Characterization of Pharmaceutical Nano- and Microsystems 

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview

Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale.

The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker.

Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines.

Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics:

* An introduction to the analytical tools applied to determine particle size, morphology, and shape

* Common chemical approaches to drug system characterization

* A description of solid-state characterization of drug systems

* Drug release and permeation studies

* Toxicity and safety issues

* The interaction of drug particles with cells

Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Mục lục

1. Selecting a Particle Sizer for the Pharmaceutical Industry

Professor Maria Margarida Figuiredo (mmf@eq.uc.pt)

2. Spectroscopic methods in solid-state characterization

Professor Clare Strachan (clare.strachan@helsinki.fi)

3. Microfluidic analysis techniques for safety assessment of pharmaceutical nano- and microsystems

Dr Tiina Sikanen(tiina.sikanen@helsinki.fi)

4. In Vitro In Vivo Correlation for Pharmaceutical Nano and Microsystems

Prof. Vandana Patravale (vbp_muict@yahoo.co.in)

5. Characterization of Bioadhesion, Mucin-interactions and Mucosal Permeability of Pharmaceutical Nano- and Microsystems

Ellen Hagesaether, Marianne Hiorth and Prof Ingunn Tho (Ingunn.tho@farmasi.uio.no)

6. Cell-Nanoparticle Interactions: Toxicity and Safety Issues

Helder Santos (helder.santos@helsinki.fi)

7. Intestinal mucosal tissue models to validate functionalized nanosystems

Bruno Sarmento (bruno.sarmento@ineb.up.pt)

8. Biodistribution of polymeric, polysaccharide and metallic nanoparticles

Erem Bilensoy (eremino@hacettepe.edu.tr)

9. Opportunities and challenges of silicon-based nanoparticles for drug delivery and imaging

Jessica Rosenholm (jessica.rosenholm@abo.fi)

10. Statistical Analysis and Multidimensional Modelling in Research Osmo Antikainen (osmo.antikainen@helsinki.fi)

Giới thiệu về tác giả

Leena Peltonen is Adjunct Professor in the Division of Pharmaceutical Chemistry and Technology at the University of Helsinki, Finland. She holds two master’s degrees, as well as a Ph D in Pharmacy that she obtained in 2001.